Consider Risk for Gadolinium Retention in the Brain When Using Gadolinium-based Contrast Media
نویسندگان
چکیده
منابع مشابه
Linear Gadolinium-Based Contrast Agents Are Associated With Brain Gadolinium Retention in Healthy Rats
OBJECTIVES The aim of this study was to evaluate Gd retention in the deep cerebellar nuclei (DCN) of linear gadolinium-based contrast agents (GBCAs) compared with a macrocyclic contrast agent. MATERIALS AND METHODS The brain tissue retention of Gd of 3 linear GBCAs (gadobenate dimeglumine, gadopentetate dimeglumine, and gadodiamide) and a macrocyclic GBCA (gadoterate meglumine) was compared i...
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Nevzat Karabulut Life is continuously confronting us with new issues and sometimes breaking our routine. One case in point is the curious way radiologists’ knowledge about the benefits and risks of gadolinium-based contrast agents (GBCAs) continues to evolve. Significantly improving detection and characterization of lesions in a broad spectrum of diseases, GBCAs have become integral aides to ma...
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OBJECTIVE Gadolinium neutron capture therapy (GdNCT) is a potential treatment for malignant tumors based on two steps: (1) injection of a tumor-specific (157)Gd compound; (2) tumor irradiation with thermal neutrons. The GdNC reaction can induce cell death provided that Gd is proximate to DNA. Here, we studied the nuclear uptake of Gd by glioblastoma (GBM) tumor cells after treatment with two Gd...
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ژورنال
عنوان ژورنال: RadioGraphics
سال: 2016
ISSN: 0271-5333,1527-1323
DOI: 10.1148/rg.2016150244